316.04 1.00 (0.32%)
10.0M
XNAS Volume
High volume today
XNAS 21 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Matthew C. Busch | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 313.71 per share. | 17 Mar 2025 | 174 | 5,117 (0%) | 0% | 313.7 | 54,586 | Common Stock |
| Derek Miller | SVP, Human Resources | Payment of exercise price or tax liability using portion of securities received from the company at price $ 313.71 per share. | 17 Mar 2025 | 930 | 9,654 (0%) | 0% | 313.7 | 291,750 | Common Stock |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 313.71 per share. | 17 Mar 2025 | 489 | 9,340 (0%) | 0% | 313.7 | 153,404 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 313.71 per share. | 17 Mar 2025 | 524 | 8,214 (0%) | 0% | 313.7 | 164,384 | Common Stock |
| Peter H. Griffith | EVP & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 313.71 per share. | 17 Mar 2025 | 3,305 | 40,334 (0%) | 0% | 313.7 | 1,036,812 | Common Stock |
| David M. Reese | EVP & Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 313.71 per share. | 17 Mar 2025 | 3,635 | 40,702 (0%) | 0% | 313.7 | 1,140,336 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 313.71 per share. | 17 Mar 2025 | 3,393 | 75,075 (0%) | 0% | 313.7 | 1,064,418 | Common Stock |
| Murdo Gordon | EVP, Global Commercial Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 313.71 per share. | 17 Mar 2025 | 4,039 | 48,386 (0%) | 0% | 313.7 | 1,267,075 | Common Stock |
| Jonathan P. Graham | EVP & Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 313.71 per share. | 17 Mar 2025 | 3,150 | 32,266 (0%) | 0% | 313.7 | 988,187 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 313.71 per share. | 17 Mar 2025 | 12,853 | 587,565 (0%) | 0% | 313.7 | 4,032,115 | Common Stock |
| Peter H. Griffith | EVP & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2025 | 7,277 | 43,502 (0%) | 0% | 0 | Common Stock | |
| Robert A. Bradway | Director, Chairman, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2025 | 25,734 | 599,925 (0%) | 0% | 0 | Common Stock | |
| Jonathan P. Graham | EVP & Gen. Counsel & Secy. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2025 | 6,306 | 35,293 (0%) | 0% | 0 | Common Stock | |
| Murdo Gordon | EVP, Global Commercial Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2025 | 8,085 | 52,271 (0%) | 0% | 0 | Common Stock | |
| Esteban Santos | EVP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2025 | 6,792 | 78,338 (0%) | 0% | 0 | Common Stock | |
| David M. Reese | EVP & Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2025 | 7,277 | 44,199 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2025 | 1,503 | 8,713 (0%) | 0% | 0 | Common Stock | |
| Rachna Khosla | SVP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2025 | 1,403 | 9,802 (0%) | 0% | 0 | Common Stock | |
| Derek Miller | SVP, Human Resources | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2025 | 2,005 | 10,549 (0%) | 0% | 0 | Common Stock | |
| Matthew C. Busch | VP, Finance & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2025 | 497 | 5,277 (0%) | 0% | 0 | Common Stock | |
| David M. Reese | EVP & Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 293.22 per share. | 19 Feb 2025 | 8,711 | 62,147 (0%) | 0% | 293.2 | 2,554,224 | Common Stock |
| David M. Reese | EVP & Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 156.35 per share. | 19 Feb 2025 | 8,711 | 70,858 (0%) | 0% | 156.4 | 1,361,965 | Common Stock |
| David M. Reese | EVP & Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 304.44 per share. | 19 Feb 2025 | 25,225 | 36,922 (0%) | 0% | 304.4 | 7,679,524 | Common Stock |
| David M. Reese | EVP & Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Feb 2025 | 8,711 | 0 | - | - | Nqso (Right to Buy) | |
| Esteban Santos | EVP, Operations | Sale of securities on an exchange or to another person at price $ 292.84 per share. | 19 Feb 2025 | 8,711 | 71,546 (0%) | 0% | 292.8 | 2,550,903 | Common Stock |
| Esteban Santos | EVP, Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Feb 2025 | 8,711 | 0 | - | - | Nqso (Right to Buy) | |
| Esteban Santos | EVP, Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 156.35 per share. | 19 Feb 2025 | 8,711 | 80,257 (0%) | 0% | 156.4 | 1,361,965 | Common Stock |
| Derek Miller | SVP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Feb 2025 | 1,524 | 0 | - | - | Nqso (Right to Buy) | |
| Derek Miller | SVP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 156.35 per share. | 18 Feb 2025 | 1,524 | 10,068 (0%) | 0% | 156.3 | 238,277 | Common Stock |
| Derek Miller | SVP, Human Resources | Sale of securities on an exchange or to another person at price $ 293.74 per share. | 18 Feb 2025 | 1,524 | 8,544 (0%) | 0% | 293.7 | 447,655 | Common Stock |
| Derek Miller | SVP, Human Resources | Sale of securities on an exchange or to another person at price $ 292.56 per share. | 18 Feb 2025 | 500 | 8,544 (0%) | 0% | 292.6 | 146,279 | Common Stock |
| Murdo Gordon | EVP, Global Commercial Ops | Sale of securities on an exchange or to another person at price $ 294.79 per share. | 11 Feb 2025 | 8,771 | 44,186 (0%) | 0% | 294.8 | 2,585,644 | Common Stock |
| Jonathan P. Graham | EVP & Gen. Counsel & Secy. | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Feb 2025 | 25,045 | 0 | - | - | Nqso (Right to Buy) | |
| Jonathan P. Graham | EVP & Gen. Counsel & Secy. | Sale of securities on an exchange or to another person at price $ 293.12 per share. | 07 Feb 2025 | 25,045 | 28,987 (0%) | 0% | 293.1 | 7,341,123 | Common Stock |
| Jonathan P. Graham | EVP & Gen. Counsel & Secy. | Exercise or conversion of derivative security received from the company (such as an option) at price $ 156.35 per share. | 07 Feb 2025 | 25,045 | 54,032 (0%) | 0% | 156.4 | 3,915,786 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Sale of securities on an exchange or to another person at price $ 304.47 per share. | 05 Feb 2025 | 1,589 | 7,210 (0%) | 0% | 304.5 | 483,808 | Common Stock |
| Graham P. Jonathan | EVP & Gen. Counsel & Secy. | Gift of securities by or to the insider at price $ 0.00 per share. | 05 Dec 2024 | 6,430 | 28,903 (0%) | 0% | 0 | Common Stock | |
| Bradway Robert A. | Director, Chairman, CEO and President | Gift of securities by or to the insider at price $ 0.00 per share. | 02 Dec 2024 | 90,000 | 393,855 (0%) | 0% | 0 | Common Stock | |
| A. Robert Bradway | Director, Chairman, CEO and President | Gift of securities by or to the insider at price $ 0.00 per share. | 02 Dec 2024 | 90,000 | 90,000 (0%) | 0% | 0 | Common Stock | |
| Bradway A. Robert | Director, Chairman, CEO and President | Gift of securities by or to the insider at price $ 0.00 per share. | 02 Dec 2024 | 96,000 | 573,855 (0%) | 0% | 0 | Common Stock | |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 316.91 per share. | 05 Nov 2024 | 212 | 8,383 (0%) | 0% | 316.9 | 67,185 | Common Stock |
| Matthew C. Busch | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 316.91 per share. | 05 Nov 2024 | 189 | 4,770 (0%) | 0% | 316.9 | 59,896 | Common Stock |
| Michael V. Drake | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Nov 2024 | 220 | 3,552 (0%) | 0% | 0 | Common Stock | |
| Charles M. Holley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Nov 2024 | 268 | 10,114 (0%) | 0% | 0 | Common Stock | |
| Michael V. Drake | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Aug 2024 | 108 | 3,307 (0%) | 0% | 0 | Common Stock | |
| Charles M. Holley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Aug 2024 | 131 | 9,776 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 333.28 per share. | 31 Jul 2024 | 1,565 | 8,771 (0%) | 0% | 333.3 | 521,583 | Common Stock |
| Brian J. Druker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2024 | 719 | 6,472 (0%) | 0% | 0 | Common Stock | |
| Amy E. Miles | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2024 | 719 | 3,927 (0%) | 0% | 0 | Common Stock | |
| Charles M. Holley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2024 | 719 | 9,574 (0%) | 0% | 0 | Common Stock | |
| Ellen J. Kullman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2024 | 719 | 12,299 (0%) | 0% | 0 | Common Stock | |
| Robert A. Eckert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2024 | 719 | 23,715 (0%) | 0% | 0 | Common Stock | |
| Tyler E. Jacks | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2024 | 719 | 16,005 (0%) | 0% | 0 | Common Stock | |
| Greg Garland | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2024 | 719 | 12,374 (0%) | 0% | 0 | Common Stock | |
| Wanda M. Austin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2024 | 719 | 6,544 (0%) | 0% | 0 | Common Stock | |
| Michael V. Drake | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2024 | 719 | 3,174 (0%) | 0% | 0 | Common Stock | |
| Mary E. Klotman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2024 | 719 | 719 (0%) | 0% | 0 | Common Stock | |
| Matthew C. Busch | VP, Finance & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 333 | 4,932 (0%) | 0% | 0 | Common Stock | |
| Matthew C. Busch | VP, Finance & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 2,163 | 2,163 | - | - | Nqso (Right to Buy) | |
| Charles M. Holley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 141 | 8,855 (0%) | 0% | 0 | Common Stock | |
| Michael V. Drake | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 116 | 2,455 (0%) | 0% | 0 | Common Stock | |
| Robert A. Bradway | Director, Chairman, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 11,988 | 669,269 (0%) | 0% | 0 | Common Stock | |
| Robert A. Bradway | Director, Chairman, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 77,877 | 77,877 | - | - | Nqso (Right to Buy) | |
| Jonathan P. Graham | EVP & Gen. Counsel & Secy. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 18,603 | 18,603 | - | - | Nqso (Right to Buy) | |
| Jonathan P. Graham | EVP & Gen. Counsel & Secy. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 2,863 | 35,186 (0%) | 0% | 0 | Common Stock | |
| Murdo Gordon | EVP, Global Commercial Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 3,529 | 52,674 (0%) | 0% | 0 | Common Stock | |
| Murdo Gordon | EVP, Global Commercial Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 22,930 | 45,860 | - | - | Nqso (Right to Buy) | |
| James E. Bradner | EVP, R&D, & Chief Sci. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 18,603 | 18,603 | - | - | Nqso (Right to Buy) | |
| James E. Bradner | EVP, R&D, & Chief Sci. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 2,863 | 25,438 (0%) | 0% | 0 | Common Stock | |
| Esteban Santos | EVP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 19,469 | 38,938 | - | - | Nqso (Right to Buy) | |
| Esteban Santos | EVP, Operations | Grant, award, or other acquisition of securities at price $ 300.30 per share. | 07 May 2024 | 2,997 | 71,304 (0%) | 0% | 300.3 | 899,999 | Common Stock |
| David M. Reese | EVP & Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 20,767 | 20,767 | - | - | Nqso (Right to Buy) | |
| David M. Reese | EVP & Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 3,196 | 61,889 (0%) | 0% | 0 | Common Stock | |
| Peter H. Griffith | EVP & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 20,767 | 20,767 | - | - | Nqso (Right to Buy) | |
| Peter H. Griffith | EVP & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 3,196 | 35,973 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 499 | 10,300 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 3,244 | 3,244 | - | - | Nqso (Right to Buy) | |
| Rachna Khosla | SVP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 3,461 | 3,461 | - | - | Nqso (Right to Buy) | |
| Rachna Khosla | SVP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 532 | 8,559 (0%) | 0% | 0 | Common Stock | |
| Derek Miller | SVP, Human Resources | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 865 | 8,983 (0%) | 0% | 0 | Common Stock | |
| Derek Miller | SVP, Human Resources | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2024 | 5,624 | 11,248 | - | - | Nqso (Right to Buy) | |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 311.29 per share. | 05 May 2024 | 2,220 | 657,281 (0%) | 0% | 311.3 | 691,064 | Common Stock |
| Jonathan P. Graham | EVP & Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 311.29 per share. | 05 May 2024 | 632 | 32,323 (0%) | 0% | 311.3 | 196,735 | Common Stock |
| Murdo Gordon | EVP, Global Commercial Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 311.29 per share. | 05 May 2024 | 665 | 49,145 (0%) | 0% | 311.3 | 207,008 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 311.29 per share. | 05 May 2024 | 617 | 68,307 (0%) | 0% | 311.3 | 192,066 | Common Stock |
| David M. Reese | EVP & Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 311.29 per share. | 05 May 2024 | 633 | 58,693 (0%) | 0% | 311.3 | 197,047 | Common Stock |
| Peter H. Griffith | EVP & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 311.29 per share. | 05 May 2024 | 648 | 32,777 (0%) | 0% | 311.3 | 201,716 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 311.29 per share. | 05 May 2024 | 82 | 9,801 (0%) | 0% | 311.3 | 25,526 | Common Stock |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 311.29 per share. | 05 May 2024 | 41 | 8,027 (0%) | 0% | 311.3 | 12,763 | Common Stock |
| Derek Miller | SVP, Human Resources | Payment of exercise price or tax liability using portion of securities received from the company at price $ 311.29 per share. | 05 May 2024 | 78 | 8,118 (0%) | 0% | 311.3 | 24,281 | Common Stock |
| Matthew C. Busch | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 311.30 per share. | 05 May 2024 | 27 | 4,599 (0%) | 0% | 311.3 | 8,405 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Sale of securities on an exchange or to another person at price $ 313.09 per share. | 03 May 2024 | 2,117 | 9,883 (0%) | 0% | 313.1 | 662,802 | Common Stock |
| Jonathan P. Graham | EVP & Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 277.37 per share. | 02 May 2024 | 591 | 32,955 (0%) | 0% | 277.4 | 163,926 | Common Stock |
| Murdo Gordon | EVP, Global Commercial Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 277.37 per share. | 02 May 2024 | 758 | 49,810 (0%) | 0% | 277.4 | 210,246 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 277.37 per share. | 02 May 2024 | 606 | 68,924 (0%) | 0% | 277.4 | 168,086 | Common Stock |
| David M. Reese | EVP & Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 277.37 per share. | 02 May 2024 | 650 | 59,326 (0%) | 0% | 277.4 | 180,291 | Common Stock |
| Peter H. Griffith | EVP & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 277.37 per share. | 02 May 2024 | 682 | 33,425 (0%) | 0% | 277.4 | 189,166 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 277.37 per share. | 02 May 2024 | 114 | 12,000 (0%) | 0% | 277.4 | 31,620 | Common Stock |
| Derek Miller | SVP, Human Resources | Payment of exercise price or tax liability using portion of securities received from the company at price $ 277.37 per share. | 02 May 2024 | 152 | 8,196 (0%) | 0% | 277.4 | 42,160 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 277.37 per share. | 02 May 2024 | 2,294 | 659,501 (0%) | 0% | 277.4 | 636,287 | Common Stock |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 277.36 per share. | 02 May 2024 | 74 | 8,068 (0%) | 0% | 277.4 | 20,525 | Common Stock |
| Matthew C. Busch | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 277.37 per share. | 02 May 2024 | 27 | 4,626 (0%) | 0% | 277.4 | 7,489 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 276.38 per share. | 30 Apr 2024 | 2,282 | 661,795 (0%) | 0% | 276.4 | 630,699 | Common Stock |
| Murdo Gordon | EVP, Global Commercial Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 276.38 per share. | 30 Apr 2024 | 753 | 50,568 (0%) | 0% | 276.4 | 208,114 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 276.38 per share. | 30 Apr 2024 | 683 | 69,530 (0%) | 0% | 276.4 | 188,768 | Common Stock |
| David M. Reese | EVP & Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 276.38 per share. | 30 Apr 2024 | 690 | 59,976 (0%) | 0% | 276.4 | 190,702 | Common Stock |
| Peter H. Griffith | EVP & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 276.38 per share. | 30 Apr 2024 | 603 | 34,107 (0%) | 0% | 276.4 | 166,657 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 276.38 per share. | 30 Apr 2024 | 106 | 12,114 (0%) | 0% | 276.4 | 29,296 | Common Stock |
| Matthew C. Busch | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 276.35 per share. | 30 Apr 2024 | 17 | 4,653 (0%) | 0% | 276.4 | 4,698 | Common Stock |
| Jonathan P. Graham | EVP & Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 276.38 per share. | 30 Apr 2024 | 686 | 33,546 (0%) | 0% | 276.4 | 189,597 | Common Stock |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 276.38 per share. | 30 Apr 2024 | 48 | 8,142 (0%) | 0% | 276.4 | 13,266 | Common Stock |
| Derek Miller | SVP, Human Resources | Payment of exercise price or tax liability using portion of securities received from the company at price $ 276.38 per share. | 30 Apr 2024 | 71 | 8,348 (0%) | 0% | 276.4 | 19,623 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 268.87 per share. | 18 Mar 2024 | 20,560 | 664,077 (0%) | 0% | 268.9 | 5,527,967 | Common Stock |
| Jonathan P. Graham | EVP & Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 268.87 per share. | 18 Mar 2024 | 5,879 | 34,232 (0%) | 0% | 268.9 | 1,580,687 | Common Stock |
| Murdo Gordon | EVP, Global Commercial Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 268.87 per share. | 18 Mar 2024 | 6,461 | 51,321 (0%) | 0% | 268.9 | 1,737,169 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 268.87 per share. | 18 Mar 2024 | 6,137 | 70,213 (0%) | 0% | 268.9 | 1,650,055 | Common Stock |
| David M. Reese | EVP & Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 268.87 per share. | 18 Mar 2024 | 6,202 | 60,666 (0%) | 0% | 268.9 | 1,667,532 | Common Stock |
| Peter H. Griffith | EVP & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 268.87 per share. | 18 Mar 2024 | 5,168 | 34,710 (0%) | 0% | 268.9 | 1,389,520 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 268.87 per share. | 18 Mar 2024 | 703 | 12,220 (0%) | 0% | 268.9 | 189,016 | Common Stock |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 268.87 per share. | 18 Mar 2024 | 438 | 8,190 (0%) | 0% | 268.9 | 117,765 | Common Stock |
| Derek Miller | SVP, Human Resources | Payment of exercise price or tax liability using portion of securities received from the company at price $ 268.87 per share. | 18 Mar 2024 | 475 | 8,419 (0%) | 0% | 268.9 | 127,713 | Common Stock |
| Matthew C. Busch | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 268.87 per share. | 18 Mar 2024 | 146 | 4,670 (0%) | 0% | 268.9 | 39,255 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2024 | 41,133 | 683,910 (0%) | 0% | 0 | Common Stock | |
| Jonathan P. Graham | EVP & Gen. Counsel & Secy. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2024 | 11,760 | 39,925 (0%) | 0% | 0 | Common Stock | |
| Murdo Gordon | EVP, Global Commercial Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2024 | 12,924 | 57,569 (0%) | 0% | 0 | Common Stock | |
| Esteban Santos | EVP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2024 | 12,278 | 76,125 (0%) | 0% | 0 | Common Stock | |
| David M. Reese | EVP & Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2024 | 12,407 | 66,653 (0%) | 0% | 0 | Common Stock | |
| Peter H. Griffith | EVP & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2024 | 10,338 | 39,250 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2024 | 1,954 | 12,866 (0%) | 0% | 0 | Common Stock | |
| Rachna Khosla | SVP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2024 | 1,256 | 8,597 (0%) | 0% | 0 | Common Stock | |
| Derek Miller | SVP, Human Resources | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2024 | 1,311 | 8,863 (0%) | 0% | 0 | Common Stock | |
| Matthew C. Busch | VP, Finance & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2024 | 418 | 4,799 (0%) | 0% | 0 | Common Stock | |
| James E. Bradner | EVP, R&D, & Chief Sci. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 13,806 | 22,393 (0%) | 0% | 0 | Common Stock | |
| Bradner James E. | EVP, R&D, & Chief Sci. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 8,587 | 8,587 (0%) | 0% | 0 | Common Stock | |
| Grygiel A. Nancy | SVP & CCO | Sale of securities on an exchange or to another person at price $ 273.03 per share. | 04 Dec 2023 | 2,096 | 10,874 (0%) | 0% | 273.0 | 572,276 | Common Stock |
| Murdo Gordon | EVP, Global Commercial Ops | Sale of securities on an exchange or to another person at price $ 262.43 per share. | 10 Aug 2023 | 9,558 | 44,308 (0%) | 0% | 262.4 | 2,508,306 | Common Stock |
| Charles M. Holley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2023 | 153 | 8,132 (0%) | 0% | 0 | Common Stock | |
| Michael V. Drake | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2023 | 124 | 2,024 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.37 per share. | 31 Jul 2023 | 1,129 | 13,095 (0%) | 0% | 236.4 | 266,862 | Common Stock |
| Amy E. Miles | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 939 | 3,115 (0%) | 0% | 0 | Common Stock | |
| Charles M. Holley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 939 | 7,978 (0%) | 0% | 0 | Common Stock | |
| Ellen J. Kullman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 939 | 11,208 (0%) | 0% | 0 | Common Stock | |
| Robert Sanders Williams | Director | 19 May 2023 | 939 | 6,240 (0%) | 0% | 0 | Common Stock | ||
| Robert A. Eckert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 939 | 22,465 (0%) | 0% | 0 | Common Stock | |
| Ronald D. Sugar | Director | 19 May 2023 | 939 | 19,682 (0%) | 0% | 0 | Common Stock | ||
| Tyler Jacks | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 939 | 14,868 (0%) | 0% | 0 | Common Stock | |
| Greg Garland | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 939 | 11,655 (0%) | 0% | 0 | Common Stock | |
| Wanda M. Austin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 939 | 5,825 (0%) | 0% | 0 | Common Stock | |
| Brian J. Druker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 939 | 5,688 (0%) | 0% | 0 | Common Stock | |
| Michael V. Drake | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 939 | 1,899 (0%) | 0% | 0 | Common Stock | |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 231.89 per share. | 05 May 2023 | 2,083 | 641,734 (0%) | 0% | 231.9 | 483,027 | Common Stock |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 231.89 per share. | 05 May 2023 | 592 | 39,573 (0%) | 0% | 231.9 | 137,279 | Common Stock |
| Murdo Gordon | EVP, Global Commercial Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 231.89 per share. | 05 May 2023 | 623 | 53,866 (0%) | 0% | 231.9 | 144,467 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 231.89 per share. | 05 May 2023 | 579 | 63,582 (0%) | 0% | 231.9 | 134,264 | Common Stock |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 231.89 per share. | 05 May 2023 | 594 | 54,114 (0%) | 0% | 231.9 | 137,743 | Common Stock |
| Peter H. Griffith | EVP & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 231.89 per share. | 05 May 2023 | 608 | 31,990 (0%) | 0% | 231.9 | 140,989 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 231.89 per share. | 05 May 2023 | 54 | 14,224 (0%) | 0% | 231.9 | 12,522 | Common Stock |
| Linda H. Louie | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 231.88 per share. | 05 May 2023 | 16 | 9,966 (0%) | 0% | 231.9 | 3,710 | Common Stock |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 231.90 per share. | 05 May 2023 | 39 | 7,581 (0%) | 0% | 231.9 | 9,044 | Common Stock |
| Derek Miller | SVP, Human Resources | Payment of exercise price or tax liability using portion of securities received from the company at price $ 231.88 per share. | 05 May 2023 | 51 | 7,553 (0%) | 0% | 231.9 | 11,826 | Common Stock |
| Charles M. Holley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 169 | 7,039 (0%) | 0% | 0 | Common Stock | |
| Robert A. Bradway | Director, Chairman, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 13,486 | 646,680 (0%) | 0% | 0 | Common Stock | |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.97 per share. | 02 May 2023 | 2,863 | 643,817 (0%) | 0% | 236.0 | 675,582 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 114,040 | 114,040 | - | - | Nqso (Right to Buy) | |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 3,390 | 40,767 (0%) | 0% | 0 | Common Stock | |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.97 per share. | 02 May 2023 | 602 | 40,165 (0%) | 0% | 236.0 | 142,054 | Common Stock |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 28,666 | 28,666 | - | - | Nqso (Right to Buy) | |
| Murdo Gordon | EVP, Global Commercial Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.97 per share. | 02 May 2023 | 859 | 54,489 (0%) | 0% | 236.0 | 202,698 | Common Stock |
| Murdo Gordon | EVP, Global Commercial Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 4,237 | 55,348 (0%) | 0% | 0 | Common Stock | |
| Murdo Gordon | EVP, Global Commercial Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 35,833 | 35,833 | - | - | Nqso (Right to Buy) | |
| Esteban Santos | EVP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 30,100 | 30,100 | - | - | Nqso (Right to Buy) | |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.97 per share. | 02 May 2023 | 716 | 64,161 (0%) | 0% | 236.0 | 168,955 | Common Stock |
| Esteban Santos | EVP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 3,559 | 64,877 (0%) | 0% | 0 | Common Stock | |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.97 per share. | 02 May 2023 | 819 | 54,708 (0%) | 0% | 236.0 | 193,259 | Common Stock |
| David M. Reese | EVP, Research and Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 3,814 | 55,527 (0%) | 0% | 0 | Common Stock | |
| David M. Reese | EVP, Research and Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 32,250 | 32,250 | - | - | Nqso (Right to Buy) | |
| Peter H. Griffith | EVP & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 3,814 | 32,598 (0%) | 0% | 0 | Common Stock | |
| Peter H. Griffith | EVP & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 32,250 | 32,250 | - | - | Nqso (Right to Buy) | |
| Nancy A. Grygiel | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 635 | 14,340 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.97 per share. | 02 May 2023 | 62 | 14,278 (0%) | 0% | 236.0 | 14,630 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 5,375 | 5,375 | - | - | Nqso (Right to Buy) | |
| Linda H. Louie | VP, Finance & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 3,583 | 3,583 | - | - | Nqso (Right to Buy) | |
| Linda H. Louie | VP, Finance & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 423 | 10,002 (0%) | 0% | 0 | Common Stock | |
| Linda H. Louie | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.95 per share. | 02 May 2023 | 20 | 9,982 (0%) | 0% | 236.0 | 4,719 | Common Stock |
| Rachna Khosla | SVP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 593 | 7,677 (0%) | 0% | 0 | Common Stock | |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.96 per share. | 02 May 2023 | 57 | 7,620 (0%) | 0% | 236.0 | 13,450 | Common Stock |
| Rachna Khosla | SVP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 5,016 | 5,016 | - | - | Nqso (Right to Buy) | |
| Derek Miller | SVP, Human Resources | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 9,316 | 9,316 | - | - | Nqso (Right to Buy) | |
| Derek Miller | SVP, Human Resources | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.96 per share. | 02 May 2023 | 57 | 7,604 (0%) | 0% | 236.0 | 13,450 | Common Stock |
| Derek Miller | SVP, Human Resources | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 1,101 | 7,661 (0%) | 0% | 0 | Common Stock | |
| Michael V. Drake | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2023 | 137 | 960 (0%) | 0% | 0 | Common Stock | |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.74 per share. | 30 Apr 2023 | 2,208 | 633,194 (0%) | 0% | 239.7 | 529,346 | Common Stock |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.74 per share. | 30 Apr 2023 | 664 | 37,377 (0%) | 0% | 239.7 | 159,187 | Common Stock |
| Murdo Gordon | EVP, Global Commercial Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.74 per share. | 30 Apr 2023 | 728 | 51,111 (0%) | 0% | 239.7 | 174,531 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.74 per share. | 30 Apr 2023 | 660 | 61,318 (0%) | 0% | 239.7 | 158,228 | Common Stock |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.74 per share. | 30 Apr 2023 | 666 | 51,713 (0%) | 0% | 239.7 | 159,667 | Common Stock |
| Peter H. Griffith | EVP & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.74 per share. | 30 Apr 2023 | 583 | 28,784 (0%) | 0% | 239.7 | 139,768 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.74 per share. | 30 Apr 2023 | 73 | 13,705 (0%) | 0% | 239.7 | 17,501 | Common Stock |
| Linda H. Louie | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.74 per share. | 30 Apr 2023 | 27 | 9,579 (0%) | 0% | 239.7 | 6,473 | Common Stock |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.74 per share. | 30 Apr 2023 | 47 | 7,084 (0%) | 0% | 239.7 | 11,268 | Common Stock |
| Derek Miller | SVP, Human Resources | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.74 per share. | 30 Apr 2023 | 50 | 6,560 (0%) | 0% | 239.7 | 11,987 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 234.57 per share. | 17 Mar 2023 | 13,971 | 635,402 (0%) | 0% | 234.6 | 3,277,177 | Common Stock |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 234.57 per share. | 17 Mar 2023 | 3,785 | 38,041 (0%) | 0% | 234.6 | 887,847 | Common Stock |
| Murdo Gordon | EVP, Global Commercial Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 234.57 per share. | 17 Mar 2023 | 3,978 | 51,839 (0%) | 0% | 234.6 | 933,119 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 234.57 per share. | 17 Mar 2023 | 3,881 | 61,978 (0%) | 0% | 234.6 | 910,366 | Common Stock |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 234.57 per share. | 17 Mar 2023 | 3,978 | 52,379 (0%) | 0% | 234.6 | 933,119 | Common Stock |
| Peter H. Griffith | EVP & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 234.57 per share. | 17 Mar 2023 | 3,403 | 29,367 (0%) | 0% | 234.6 | 798,242 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 234.57 per share. | 17 Mar 2023 | 339 | 13,778 (0%) | 0% | 234.6 | 79,519 | Common Stock |
| Linda H. Louie | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 234.57 per share. | 17 Mar 2023 | 96 | 9,606 (0%) | 0% | 234.6 | 22,519 | Common Stock |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 234.57 per share. | 17 Mar 2023 | 241 | 7,103 (0%) | 0% | 234.6 | 56,531 | Common Stock |
| Derek Miller | SVP, Human Resources | Payment of exercise price or tax liability using portion of securities received from the company at price $ 234.57 per share. | 17 Mar 2023 | 322 | 6,610 (0%) | 0% | 234.6 | 75,532 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2023 | 27,915 | 648,712 (0%) | 0% | 0 | Common Stock | |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2023 | 7,560 | 41,620 (0%) | 0% | 0 | Common Stock | |
| Murdo Gordon | EVP Global Commercial Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2023 | 7,947 | 55,621 (0%) | 0% | 0 | Common Stock | |
| Esteban Santos | EVP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2023 | 7,753 | 65,676 (0%) | 0% | 0 | Common Stock | |
| David M. Reese | EVP, Research and Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2023 | 7,947 | 56,167 (0%) | 0% | 0 | Common Stock | |
| Peter H. Griffith | EVP & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2023 | 7,753 | 32,541 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2023 | 968 | 14,032 (0%) | 0% | 0 | Common Stock | |
| Linda H. Louie | VP, Finance & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2023 | 387 | 9,679 (0%) | 0% | 0 | Common Stock | |
| Rachna Khosla | SVP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2023 | 687 | 7,338 (0%) | 0% | 0 | Common Stock | |
| Derek Miller | SVP, Human Resources | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2023 | 920 | 6,905 (0%) | 0% | 0 | Common Stock | |
| Rachna Khosla | SVP, Business Development | Sale of securities on an exchange or to another person at price $ 292.90 per share. | 09 Nov 2022 | 387 | 6,630 (0%) | 0% | 292.9 | 113,352 | Common Stock |
| Ellen J. Kullman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Nov 2022 | 222 | 10,112 (0%) | 0% | 0 | Common Stock | |
| Michael V. Drake | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Nov 2022 | 171 | 810 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 269.04 per share. | 05 Nov 2022 | 240 | 13,554 (0%) | 0% | 269.0 | 64,570 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Sale of securities on an exchange or to another person at price $ 293.54 per share. | 05 Nov 2022 | 545 | 13,009 (0%) | 0% | 293.5 | 159,977 | Common Stock |
| Linda H. Louie | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 269.04 per share. | 05 Nov 2022 | 45 | 9,278 (0%) | 0% | 269.0 | 12,107 | Common Stock |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 269.04 per share. | 05 Nov 2022 | 168 | 7,017 (0%) | 0% | 269.0 | 45,199 | Common Stock |
| Derek Miller | SVP, Human Resources | Payment of exercise price or tax liability using portion of securities received from the company at price $ 269.05 per share. | 05 Nov 2022 | 63 | 5,973 (0%) | 0% | 269.0 | 16,950 | Common Stock |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 272.06 per share. | 02 Nov 2022 | 2,440 | 48,136 (0%) | 0% | 272.1 | 663,826 | Common Stock |
| Linda H. Louie | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 272.06 per share. | 02 Nov 2022 | 125 | 9,323 (0%) | 0% | 272.1 | 34,008 | Common Stock |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 270.35 per share. | 01 Nov 2022 | 1,644 | 33,963 (0%) | 0% | 270.3 | 444,455 | Common Stock |
| Peter H. Griffith | EVP & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 270.35 per share. | 01 Nov 2022 | 3,030 | 24,675 (0%) | 0% | 270.4 | 819,161 | Common Stock |
| Robert Sanders Williams | Director | 22 Aug 2022 | 200 | 5,301 (0%) | 0% | 250.0 | 49,992 | Common Stock | |
| Murdo Gordon | EVP Global Commercial Ops | Gift of securities by or to the insider at price $ 0.00 per share. | 22 Aug 2022 | 400 | 47,484 (0%) | 0% | 0 | Common Stock | |
| Robert A. Eckert | Director | Sale of securities on an exchange or to another person at price $ 249.00 per share. | 18 Aug 2022 | 6,600 | 21,184 (0%) | 0% | 249.0 | 1,643,378 | Common Stock |
| Robert A. Eckert | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 252.09 per share. | 10 Aug 2022 | 6,791 | 27,784 (0%) | 0% | 252.1 | 1,711,943 | Common Stock |
| Robert A. Eckert | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Aug 2022 | 20,000 | 0 | - | - | Nqso (Right to Buy) | |
| Robert A. Eckert | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 85.59 per share. | 10 Aug 2022 | 20,000 | 34,575 (0%) | 0% | 85.6 | 1,711,800 | Common Stock |
| Ellen J. Kullman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Aug 2022 | 130 | 9,814 (0%) | 0% | 0 | Common Stock | |
| Michael V. Drake | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Aug 2022 | 634 | 634 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 247.47 per share. | 31 Jul 2022 | 1,229 | 13,728 (0%) | 0% | 247.5 | 304,141 | Common Stock |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 247.47 per share. | 31 Jul 2022 | 217 | 7,158 (0%) | 0% | 247.5 | 53,701 | Common Stock |
| Robert Sanders Williams | Director | 23 May 2022 | 600 | 5,501 (0%) | 0% | 250 | 150,000 | Common Stock | |
| Amy E. Miles | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2022 | 855 | 2,120 (0%) | 0% | 0 | Common Stock | |
| Charles M. Holley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2022 | 855 | 6,654 (0%) | 0% | 0 | Common Stock | |
| Ellen J. Kullman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2022 | 855 | 9,607 (0%) | 0% | 0 | Common Stock | |
| Robert Sanders Williams | Director | 17 May 2022 | 855 | 6,101 (0%) | 0% | 0 | Common Stock | ||
| Robert A. Eckert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2022 | 855 | 14,461 (0%) | 0% | 0 | Common Stock | |
| Ronald D. Sugar | Director | 17 May 2022 | 855 | 18,156 (0%) | 0% | 0 | Common Stock | ||
| Tyler Jacks | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2022 | 855 | 13,579 (0%) | 0% | 0 | Common Stock | |
| Greg Garland | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2022 | 855 | 10,716 (0%) | 0% | 0 | Common Stock | |
| Wanda M. Austin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2022 | 855 | 4,886 (0%) | 0% | 0 | Common Stock | |
| Brian J. Druker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2022 | 855 | 4,600 (0%) | 0% | 0 | Common Stock | |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Gift of securities by or to the insider at price $ 0.00 per share. | 12 May 2022 | 2,000 | 35,333 (0%) | 0% | 0 | Common Stock | |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Sale of securities on an exchange or to another person at price $ 241.81 per share. | 10 May 2022 | 13,500 | 37,333 (0%) | 0% | 241.8 | 3,264,454 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.10 per share. | 05 May 2022 | 2,017 | 619,841 (0%) | 0% | 236.1 | 476,214 | Common Stock |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.10 per share. | 05 May 2022 | 574 | 50,833 (0%) | 0% | 236.1 | 135,521 | Common Stock |
| Murdo Gordon | EVP Global Commercial Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.10 per share. | 05 May 2022 | 603 | 47,784 (0%) | 0% | 236.1 | 142,368 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.10 per share. | 05 May 2022 | 589 | 57,661 (0%) | 0% | 236.1 | 139,063 | Common Stock |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.10 per share. | 05 May 2022 | 575 | 50,307 (0%) | 0% | 236.1 | 135,758 | Common Stock |
| Peter H. Griffith | EVP & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.10 per share. | 05 May 2022 | 589 | 27,340 (0%) | 0% | 236.1 | 139,063 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.10 per share. | 05 May 2022 | 52 | 14,869 (0%) | 0% | 236.1 | 12,277 | Common Stock |
| Linda H. Louie | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.13 per share. | 05 May 2022 | 15 | 9,404 (0%) | 0% | 236.1 | 3,542 | Common Stock |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.11 per share. | 05 May 2022 | 37 | 7,344 (0%) | 0% | 236.1 | 8,736 | Common Stock |
| Derek Miller | SVP, Human Resources | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.10 per share. | 05 May 2022 | 49 | 6,006 (0%) | 0% | 236.1 | 11,569 | Common Stock |
| Ellen J. Kullman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 140 | 8,752 (0%) | 0% | 0 | Common Stock | |
| Robert A. Bradway | Director, Chairman, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 13,781 | 624,550 (0%) | 0% | 0 | Common Stock | |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 230.92 per share. | 02 May 2022 | 2,692 | 621,858 (0%) | 0% | 230.9 | 621,637 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 112,508 | 112,508 | - | - | Nqso (Right to Buy) | |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 27,574 | 27,574 | - | - | Nqso (Right to Buy) | |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 230.92 per share. | 02 May 2022 | 566 | 51,407 (0%) | 0% | 230.9 | 130,701 | Common Stock |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 3,377 | 51,973 (0%) | 0% | 0 | Common Stock | |
| Murdo Gordon | EVP Global Commercial Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 35,352 | 70,704 | - | - | Nqso (Right to Buy) | |
| Murdo Gordon | EVP Global Commercial Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 4,330 | 49,195 (0%) | 0% | 0 | Common Stock | |
| Murdo Gordon | EVP Global Commercial Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 230.92 per share. | 02 May 2022 | 808 | 48,387 (0%) | 0% | 230.9 | 186,583 | Common Stock |
| Esteban Santos | EVP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 3,637 | 58,958 (0%) | 0% | 0 | Common Stock | |
| Esteban Santos | EVP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 29,695 | 29,695 | - | - | Nqso (Right to Buy) | |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 230.92 per share. | 02 May 2022 | 708 | 58,250 (0%) | 0% | 230.9 | 163,491 | Common Stock |
| David M. Reese | EVP, Research and Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 3,897 | 51,652 (0%) | 0% | 0 | Common Stock | |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 230.92 per share. | 02 May 2022 | 770 | 50,882 (0%) | 0% | 230.9 | 177,808 | Common Stock |
| David M. Reese | EVP, Research and Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 31,817 | 31,817 | - | - | Nqso (Right to Buy) | |
| Peter H. Griffith | EVP & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 02 May 2022 | 31,817 | 31,817 | - | - | Nqso (Right to Buy) | |
| Peter H. Griffith | EVP & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 3,897 | 27,929 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 5,302 | 5,302 | - | - | Nqso (Right to Buy) | |
| Nancy A. Grygiel | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 649 | 14,978 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 230.91 per share. | 02 May 2022 | 57 | 14,921 (0%) | 0% | 230.9 | 13,162 | Common Stock |
| Linda H. Louie | VP, Finance & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 433 | 9,437 (0%) | 0% | 0 | Common Stock | |
| Linda H. Louie | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 230.94 per share. | 02 May 2022 | 18 | 9,419 (0%) | 0% | 230.9 | 4,157 | Common Stock |
| Linda H. Louie | VP, Finance & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 3,535 | 3,535 | - | - | Nqso (Right to Buy) | |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 230.92 per share. | 02 May 2022 | 53 | 7,381 (0%) | 0% | 230.9 | 12,239 | Common Stock |
| Rachna Khosla | SVP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 4,949 | 4,949 | - | - | Nqso (Right to Buy) | |
| Rachna Khosla | SVP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 606 | 7,434 (0%) | 0% | 0 | Common Stock | |
| Derek Miller | SVP, Human Resources | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 7,070 | 7,070 | - | - | Nqso (Right to Buy) | |
| Derek Miller | SVP, Human Resources | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 866 | 6,109 (0%) | 0% | 0 | Common Stock | |
| Derek Miller | SVP, Human Resources | Payment of exercise price or tax liability using portion of securities received from the company at price $ 230.93 per share. | 02 May 2022 | 54 | 6,055 (0%) | 0% | 230.9 | 12,470 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 249.87 per share. | 27 Apr 2022 | 2,547 | 610,769 (0%) | 0% | 249.9 | 636,419 | Common Stock |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 249.87 per share. | 27 Apr 2022 | 599 | 48,596 (0%) | 0% | 249.9 | 149,672 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 249.87 per share. | 27 Apr 2022 | 599 | 55,321 (0%) | 0% | 249.9 | 149,672 | Common Stock |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 249.87 per share. | 27 Apr 2022 | 184 | 47,755 (0%) | 0% | 249.9 | 45,976 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 249.87 per share. | 27 Apr 2022 | 60 | 14,329 (0%) | 0% | 249.9 | 14,992 | Common Stock |
| Linda H. Louie | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 249.88 per share. | 27 Apr 2022 | 17 | 9,004 (0%) | 0% | 249.9 | 4,248 | Common Stock |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 249.86 per share. | 27 Apr 2022 | 28 | 6,828 (0%) | 0% | 249.9 | 6,996 | Common Stock |
| Derek Miller | SVP, Human Resources | Payment of exercise price or tax liability using portion of securities received from the company at price $ 249.87 per share. | 27 Apr 2022 | 273 | 5,243 (0%) | 0% | 249.9 | 68,215 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.86 per share. | 18 Mar 2022 | 17,481 | 613,316 (0%) | 0% | 235.9 | 4,123,069 | Common Stock |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.86 per share. | 18 Mar 2022 | 3,496 | 49,195 (0%) | 0% | 235.9 | 824,567 | Common Stock |
| Murdo Gordon | EVP Global Commercial Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.86 per share. | 18 Mar 2022 | 4,995 | 44,865 (0%) | 0% | 235.9 | 1,178,121 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.86 per share. | 18 Mar 2022 | 4,370 | 55,920 (0%) | 0% | 235.9 | 1,030,708 | Common Stock |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.86 per share. | 18 Mar 2022 | 4,995 | 47,939 (0%) | 0% | 235.9 | 1,178,121 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.86 per share. | 18 Mar 2022 | 350 | 14,389 (0%) | 0% | 235.9 | 82,551 | Common Stock |
| Linda H. Louie | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.86 per share. | 18 Mar 2022 | 108 | 9,021 (0%) | 0% | 235.9 | 25,473 | Common Stock |
| Rachna Khosla | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.86 per share. | 18 Mar 2022 | 322 | 6,856 (0%) | 0% | 235.9 | 75,947 | Common Stock |
| Derek Miller | SVP, Human Resources | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.86 per share. | 18 Mar 2022 | 327 | 5,516 (0%) | 0% | 235.9 | 77,126 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 34,964 | 630,141 (0%) | 0% | 0 | Common Stock | |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 6,992 | 52,487 (0%) | 0% | 0 | Common Stock | |
| Lori A Johnston | EVP, HR | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 4,495 | 40,881 (0%) | 0% | 0 | Common Stock | |
| Murdo Gordon | EVP Global Commercial Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 9,989 | 49,682 (0%) | 0% | 0 | Common Stock | |
| Esteban Santos | EVP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 8,740 | 60,119 (0%) | 0% | 0 | Common Stock | |
| David M. Reese | EVP, Research and Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 9,989 | 52,714 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 1,001 | 14,638 (0%) | 0% | 0 | Common Stock | |
| Linda H. Louie | VP, Finance & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 436 | 9,104 (0%) | 0% | 0 | Common Stock | |
| Rachna Khosla | SVP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 923 | 7,139 (0%) | 0% | 0 | Common Stock | |
| Charles M. Holley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Aug 2021 | 347 | 5,473 (0%) | 0% | 0 | Common Stock | |
| Ellen J. Kullman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Aug 2021 | 282 | 8,263 (0%) | 0% | 0 | Common Stock | |
| Amy E. Miles | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2021 | 837 | 1,245 (0%) | 0% | 0 | Common Stock | |
| Charles M. Holley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2021 | 837 | 5,093 (0%) | 0% | 0 | Common Stock | |
| Ellen J. Kullman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2021 | 837 | 7,930 (0%) | 0% | 0 | Common Stock | |
| Robert Sanders Williams | Director | 18 May 2021 | 837 | 5,246 (0%) | 0% | 0 | Common Stock | ||
| Robert A. Eckert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2021 | 837 | 13,199 (0%) | 0% | 0 | Common Stock | |
| Ronald D. Sugar | Director | 18 May 2021 | 837 | 16,764 (0%) | 0% | 0 | Common Stock | ||
| Tyler Jacks | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2021 | 837 | 12,410 (0%) | 0% | 0 | Common Stock | |
| Greg Garland | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2021 | 837 | 9,861 (0%) | 0% | 0 | Common Stock | |
| Wanda M. Austin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2021 | 837 | 4,031 (0%) | 0% | 0 | Common Stock | |
| Brian J. Druker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2021 | 837 | 3,634 (0%) | 0% | 0 | Common Stock | |
| Ronald D. Sugar | Director | 12 May 2021 | 1,000 | 16,927 (0%) | 0% | 71.6 | 71,640 | Common Stock | |
| Ronald D. Sugar | Director | 12 May 2021 | 1,000 | 0 | - | - | Nqso (Right to Buy) | ||
| Ronald D. Sugar | Director | 12 May 2021 | 1,000 | 15,927 (0%) | 0% | 250.6 | 250,590 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 May 2021 | 2,500 | 1,639 | - | - | Nqso (Right to Buy) | |
| Nancy A. Grygiel | SVP & CCO | Sale of securities on an exchange or to another person at price $ 252.51 per share. | 11 May 2021 | 2,500 | 12,461 (0%) | 0% | 252.5 | 631,272 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 162.60 per share. | 11 May 2021 | 2,500 | 14,961 (0%) | 0% | 162.6 | 406,500 | Common Stock |
| Robert Sanders Williams | Director | 07 May 2021 | 250 | 4,409 (0%) | 0% | 251.8 | 62,945 | Common Stock | |
| Charles M. Holley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 166 | 4,256 (0%) | 0% | 0 | Common Stock | |
| Ellen J. Kullman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 135 | 7,093 (0%) | 0% | 0 | Common Stock | |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.64 per share. | 30 Apr 2021 | 2,902 | 597,023 (0%) | 0% | 239.6 | 695,435 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.64 per share. | 30 Apr 2021 | 2,850 | 594,173 (0%) | 0% | 239.6 | 682,974 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 115,307 | 115,307 | - | - | Nqso (Right to Buy) | |
| Robert A. Bradway | Director, Chairman, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 13,280 | 599,925 (0%) | 0% | 0 | Common Stock | |
| David A. Piacquad | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.64 per share. | 30 Apr 2021 | 220 | 44,787 (0%) | 0% | 239.6 | 52,721 | Common Stock |
| David A. Piacquad | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.64 per share. | 30 Apr 2021 | 139 | 45,007 (0%) | 0% | 239.6 | 33,310 | Common Stock |
| David A. Piacquad | SVP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 709 | 45,146 (0%) | 0% | 0 | Common Stock | |
| David A. Piacquad | SVP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 6,159 | 6,159 | - | - | Nqso (Right to Buy) | |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.64 per share. | 30 Apr 2021 | 581 | 47,181 (0%) | 0% | 239.6 | 139,231 | Common Stock |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 3,797 | 47,762 (0%) | 0% | 0 | Common Stock | |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 32,971 | 32,971 | - | - | Nqso (Right to Buy) | |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.64 per share. | 30 Apr 2021 | 548 | 46,633 (0%) | 0% | 239.6 | 131,323 | Common Stock |
| Lori A Johnston | EVP, HR | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.64 per share. | 30 Apr 2021 | 355 | 37,700 (0%) | 0% | 239.6 | 85,072 | Common Stock |
| Lori A Johnston | EVP, HR | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.64 per share. | 30 Apr 2021 | 335 | 37,365 (0%) | 0% | 239.6 | 80,279 | Common Stock |
| Lori A Johnston | EVP, HR | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 28,623 | 28,623 | - | - | Nqso (Right to Buy) | |
| Lori A Johnston | EVP, HR | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 3,296 | 38,055 (0%) | 0% | 0 | Common Stock | |
| Murdo Gordon | EVP Global Commercial Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.64 per share. | 30 Apr 2021 | 782 | 44,848 (0%) | 0% | 239.6 | 187,398 | Common Stock |
| Murdo Gordon | EVP Global Commercial Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 4,172 | 45,630 (0%) | 0% | 0 | Common Stock | |
| Murdo Gordon | EVP Global Commercial Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 36,231 | 36,231 | - | - | Nqso (Right to Buy) | |
| Esteban Santos | EVP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 34,420 | 34,420 | - | - | Nqso (Right to Buy) | |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.64 per share. | 30 Apr 2021 | 651 | 51,793 (0%) | 0% | 239.6 | 156,006 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.64 per share. | 30 Apr 2021 | 685 | 51,108 (0%) | 0% | 239.6 | 164,153 | Common Stock |
| Esteban Santos | EVP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 3,964 | 52,444 (0%) | 0% | 0 | Common Stock | |
| David M. Reese | EVP, Research and Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 4,006 | 46,326 (0%) | 0% | 0 | Common Stock | |
| David M. Reese | EVP, Research and Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 34,782 | 34,782 | - | - | Nqso (Right to Buy) | |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.64 per share. | 30 Apr 2021 | 745 | 44,472 (0%) | 0% | 239.6 | 178,532 | Common Stock |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.64 per share. | 30 Apr 2021 | 1,109 | 45,217 (0%) | 0% | 239.6 | 265,761 | Common Stock |
| Peter H. Griffith | EVP & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 28,985 | 28,985 | - | - | Nqso (Right to Buy) | |
| Peter H. Griffith | EVP & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 3,338 | 25,960 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.64 per share. | 30 Apr 2021 | 55 | 12,461 (0%) | 0% | 239.6 | 13,180 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.65 per share. | 30 Apr 2021 | 62 | 12,516 (0%) | 0% | 239.6 | 14,858 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 5,072 | 5,072 | - | - | Nqso (Right to Buy) | |
| Nancy A. Grygiel | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 584 | 12,578 (0%) | 0% | 0 | Common Stock | |
| Linda H. Louie | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.67 per share. | 30 Apr 2021 | 18 | 8,283 (0%) | 0% | 239.7 | 4,314 | Common Stock |
| Linda H. Louie | VP, Finance & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 300 | 8,301 (0%) | 0% | 0 | Common Stock | |
| Linda H. Louie | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.65 per share. | 30 Apr 2021 | 17 | 8,266 (0%) | 0% | 239.6 | 4,074 | Common Stock |
| Linda H. Louie | VP, Finance & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 2,608 | 2,608 | - | - | Nqso (Right to Buy) | |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 255.52 per share. | 27 Apr 2021 | 2,617 | 586,645 (0%) | 0% | 255.5 | 668,696 | Common Stock |
| David A. Piacquad | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 255.52 per share. | 27 Apr 2021 | 128 | 44,437 (0%) | 0% | 255.5 | 32,707 | Common Stock |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 255.52 per share. | 27 Apr 2021 | 564 | 43,965 (0%) | 0% | 255.5 | 144,113 | Common Stock |
| Lori A Johnston | EVP, HR | Payment of exercise price or tax liability using portion of securities received from the company at price $ 255.52 per share. | 27 Apr 2021 | 345 | 34,759 (0%) | 0% | 255.5 | 88,154 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 255.52 per share. | 27 Apr 2021 | 564 | 48,480 (0%) | 0% | 255.5 | 144,113 | Common Stock |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 255.52 per share. | 27 Apr 2021 | 174 | 42,320 (0%) | 0% | 255.5 | 44,460 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 255.53 per share. | 27 Apr 2021 | 57 | 11,994 (0%) | 0% | 255.5 | 14,565 | Common Stock |
| Linda H. Louie | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 255.50 per share. | 27 Apr 2021 | 16 | 8,001 (0%) | 0% | 255.5 | 4,088 | Common Stock |
| Ronald D. Sugar | Director | 14 Apr 2021 | 1,000 | 1,000 | - | - | Nqso (Right to Buy) | ||
| Ronald D. Sugar | Director | 14 Apr 2021 | 1,000 | 15,927 (0%) | 0% | 250.0 | 249,980 | Common Stock | |
| Ronald D. Sugar | Director | 14 Apr 2021 | 1,000 | 16,927 (0%) | 0% | 71.6 | 71,640 | Common Stock | |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 244.42 per share. | 19 Mar 2021 | 21,190 | 589,262 (0%) | 0% | 244.4 | 5,179,260 | Common Stock |
| David A. Piacquad | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 244.42 per share. | 19 Mar 2021 | 991 | 44,565 (0%) | 0% | 244.4 | 242,220 | Common Stock |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 244.42 per share. | 19 Mar 2021 | 4,360 | 44,529 (0%) | 0% | 244.4 | 1,065,671 | Common Stock |
| Lori A Johnston | EVP, HR | Payment of exercise price or tax liability using portion of securities received from the company at price $ 244.42 per share. | 19 Mar 2021 | 2,803 | 35,104 (0%) | 0% | 244.4 | 685,109 | Common Stock |
| Murdo Gordon | EVP Global Commercial Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 244.42 per share. | 19 Mar 2021 | 8,989 | 41,458 (0%) | 0% | 244.4 | 2,197,091 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 244.42 per share. | 19 Mar 2021 | 4,360 | 49,044 (0%) | 0% | 244.4 | 1,065,671 | Common Stock |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 244.42 per share. | 19 Mar 2021 | 1,401 | 42,494 (0%) | 0% | 244.4 | 342,432 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 244.42 per share. | 19 Mar 2021 | 435 | 12,051 (0%) | 0% | 244.4 | 106,323 | Common Stock |
| Linda H. Louie | VP, Finance & CAO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 244.42 per share. | 19 Mar 2021 | 115 | 8,017 (0%) | 0% | 244.4 | 28,108 | Common Stock |
| Ronald D. Sugar | Director | 10 Mar 2021 | 1,000 | 16,805 (0%) | 0% | 71.6 | 71,640 | Common Stock | |
| Ronald D. Sugar | Director | 10 Mar 2021 | 1,000 | 2,000 | - | - | Nqso (Right to Buy) | ||
| Ronald D. Sugar | Director | 10 Mar 2021 | 1,000 | 15,805 (0%) | 0% | 231.5 | 231,530 | Common Stock | |
| Robert A. Bradway | Director, Chairman, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2021 | 38,953 | 609,806 (0%) | 0% | 0 | Common Stock | |
| David A. Piacquad | SVP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2021 | 2,648 | 45,504 (0%) | 0% | 0 | Common Stock | |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2021 | 8,725 | 48,670 (0%) | 0% | 0 | Common Stock | |
| Lori A Johnston | EVP, HR | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2021 | 5,608 | 37,682 (0%) | 0% | 0 | Common Stock | |
| Murdo Gordon | EVP Global Commercial Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2021 | 17,989 | 50,159 (0%) | 0% | 0 | Common Stock | |
| Esteban Santos | EVP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2021 | 8,725 | 53,251 (0%) | 0% | 0 | Common Stock | |
| David M. Reese | EVP, Research and Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2021 | 2,803 | 43,715 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2021 | 1,245 | 12,401 (0%) | 0% | 0 | Common Stock | |
| Linda H. Louie | VP, Finance & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2021 | 467 | 8,113 (0%) | 0% | 0 | Common Stock | |
| Robert A. Bradway | Director, Chairman, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 54.69 per share. | 18 Feb 2021 | 73,500 | 618,380 (0%) | 0% | 54.7 | 4,019,715 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Feb 2021 | 73,500 | 0 | - | - | Nqso (Right to Buy) | |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 235.61 per share. | 18 Feb 2021 | 47,527 | 570,853 (0%) | 0% | 235.6 | 11,197,836 | Common Stock |
| David M. Reese | EVP, Research and Development | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Feb 2021 | 2,300 | 0 | - | - | Nqso (Right to Buy) | |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 237.21 per share. | 16 Feb 2021 | 1,147 | 40,912 (0%) | 0% | 237.2 | 272,080 | Common Stock |
| David M. Reese | EVP, Research and Development | Exercise or conversion of derivative security received from the company (such as an option) at price $ 54.69 per share. | 16 Feb 2021 | 2,300 | 42,059 (0%) | 0% | 54.7 | 125,787 | Common Stock |
| Ronald D. Sugar | Director | 10 Feb 2021 | 1,000 | 16,805 (0%) | 0% | 71.6 | 71,640 | Common Stock | |
| Ronald D. Sugar | Director | 10 Feb 2021 | 1,000 | 3,000 | - | - | Nqso (Right to Buy) | ||
| Ronald D. Sugar | Director | 10 Feb 2021 | 1,000 | 15,805 (0%) | 0% | 238.4 | 238,400 | Common Stock | |
| Robert Sanders Williams | Director | 08 Feb 2021 | 250 | 4,659 (0%) | 0% | 238.0 | 59,498 | Common Stock | |
| Lori A Johnston | EVP, HR | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.32 per share. | 07 Feb 2021 | 474 | 32,074 (0%) | 0% | 236.3 | 112,016 | Common Stock |
| Ellen J. Kullman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2021 | 16 | 6,908 (0%) | 0% | 0 | Common Stock | |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Sale of securities on an exchange or to another person at price $ 236.51 per share. | 04 Feb 2021 | 11,110 | 39,945 (0%) | 0% | 236.5 | 2,627,625 | Common Stock |
| Ronald D. Sugar | Director | 13 Jan 2021 | 1,000 | 4,000 | - | - | Nqso (Right to Buy) | ||
| Ronald D. Sugar | Director | 13 Jan 2021 | 1,000 | 16,805 (0%) | 0% | 71.6 | 71,640 | Common Stock | |
| Ronald D. Sugar | Director | 13 Jan 2021 | 1,000 | 15,805 (0%) | 0% | 236.0 | 235,990 | Common Stock | |
| Robert Sanders Williams | Director | 09 Nov 2020 | 250 | 4,909 (0%) | 0% | 242.4 | 60,600 | Common Stock | |
| Ellen J. Kullman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Nov 2020 | 140 | 6,846 (0%) | 0% | 0 | Common Stock | |
| Murdo Gordon | EVP Global Commercial Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 216.94 per share. | 02 Nov 2020 | 6,269 | 32,036 (0%) | 0% | 216.9 | 1,359,997 | Common Stock |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 216.94 per share. | 02 Nov 2020 | 2,125 | 39,619 (0%) | 0% | 216.9 | 460,998 | Common Stock |
| Linda H. Louie | VP, Finance & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Nov 2020 | 1,453 | 7,632 (0%) | 0% | 0 | Common Stock | |
| Ronald D. Sugar | Director | 19 Aug 2020 | 1,000 | 16,589 (0%) | 0% | 54.7 | 54,690 | Common Stock | |
| Ronald D. Sugar | Director | 19 Aug 2020 | 1,000 | 5,000 | - | - | Nqso (Right to Buy) | ||
| Ronald D. Sugar | Director | 19 Aug 2020 | 1,000 | 15,589 (0%) | 0% | 241.0 | 241,020 | Common Stock | |
| Robert Sanders Williams | Director | 07 Aug 2020 | 250 | 5,159 (0%) | 0% | 243.0 | 60,738 | Common Stock | |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 244.67 per share. | 01 Aug 2020 | 2,165 | 44,376 (0%) | 0% | 244.7 | 529,711 | Common Stock |
| Amy E. Miles | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Jul 2020 | 408 | 408 (0%) | 0% | 0 | Common Stock | |
| Ellen J. Kullman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Jul 2020 | 241 | 6,663 (0%) | 0% | 0 | Common Stock | |
| Nancy A. Grygiel | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 244.67 per share. | 31 Jul 2020 | 290 | 11,026 (0%) | 0% | 244.7 | 70,954 | Common Stock |
| Nancy A. Grygiel | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Jul 2020 | 8,174 | 11,316 (0%) | 0% | 0 | Common Stock | |
| Ronald D. Sugar | Director | 22 Jul 2020 | 1,000 | 15,589 (0%) | 0% | 259.8 | 259,790 | Common Stock | |
| Ronald D. Sugar | Director | 22 Jul 2020 | 1,000 | 6,000 | - | - | Nqso (Right to Buy) | ||
| Ronald D. Sugar | Director | 22 Jul 2020 | 1,000 | 16,589 (0%) | 0% | 54.7 | 54,690 | Common Stock | |
| Ronald D. Sugar | Director | 17 Jun 2020 | 1,000 | 7,000 | - | - | Nqso (Right to Buy) | ||
| Ronald D. Sugar | Director | 17 Jun 2020 | 1,000 | 15,576 (0%) | 0% | 228.5 | 228,540 | Common Stock | |
| Ronald D. Sugar | Director | 17 Jun 2020 | 1,000 | 16,576 (0%) | 0% | 54.7 | 54,690 | Common Stock | |
| Ronald D. Sugar | Director | 20 May 2020 | 1,000 | 16,482 (0%) | 0% | 54.7 | 54,690 | Common Stock | |
| Ronald D. Sugar | Director | 20 May 2020 | 1,000 | 8,000 | - | - | Nqso (Right to Buy) | ||
| Ronald D. Sugar | Director | 20 May 2020 | 1,000 | 15,482 (0%) | 0% | 229.3 | 229,270 | Common Stock | |
| Charles M. Holley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 846 | 3,974 (0%) | 0% | 0 | Common Stock | |
| Ellen J. Kullman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 977 | 6,380 (0%) | 0% | 0 | Common Stock | |
| Fred Hassan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 846 | 9,191 (0%) | 0% | 0 | Common Stock | |
| Robert Sanders Williams | Director | 05 May 2020 | 846 | 5,834 (0%) | 0% | 0 | Common Stock | ||
| Robert Sanders Williams | Director | 05 May 2020 | 425 | 5,409 (0%) | 0% | 237.3 | 100,857 | Common Stock | |
| Robert A. Eckert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 846 | 12,031 (0%) | 0% | 0 | Common Stock | |
| Robert A. Bradway | Director, Chairman, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 102,031 | 102,031 | - | - | Nqso (Right to Buy) | |
| Robert A. Bradway | Director, Chairman, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 12,184 | 543,966 (0%) | 0% | 0 | Common Stock | |
| Ronald D. Sugar | Director | 05 May 2020 | 846 | 15,482 (0%) | 0% | 0 | Common Stock | ||
| Rebecca M. Henderson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 968 | 17,973 (0%) | 0% | 0 | Common Stock | |
| Tyler Jacks | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 846 | 11,302 (0%) | 0% | 0 | Common Stock | |
| David A. Piacquad | SVP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 10,628 | 10,628 | - | - | Nqso (Right to Buy) | |
| David A. Piacquad | SVP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 1,269 | 42,773 (0%) | 0% | 0 | Common Stock | |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 3,300 | 50,656 (0%) | 0% | 0 | Common Stock | |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 27,633 | 27,633 | - | - | Nqso (Right to Buy) | |
| Greg Garland | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 846 | 9,024 (0%) | 0% | 0 | Common Stock | |
| Lori A Johnston | EVP, HR | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 2,961 | 32,268 (0%) | 0% | 0 | Common Stock | |
| Lori A Johnston | EVP, HR | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 24,799 | 24,799 | - | - | Nqso (Right to Buy) | |
| Cynthia M. Patton | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 676 | 24,751 (0%) | 0% | 0 | Common Stock | |
| Cynthia M. Patton | SVP & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 5,668 | 5,668 | - | - | Nqso (Right to Buy) | |
| Murdo Gordon | EVP Global Commercial Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 29,050 | 29,050 | - | - | Nqso (Right to Buy) | |
| Murdo Gordon | EVP Global Commercial Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 3,469 | 37,873 (0%) | 0% | 0 | Common Stock | |
| Esteban Santos | EVP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 3,384 | 46,433 (0%) | 0% | 0 | Common Stock | |
| Esteban Santos | EVP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 28,341 | 28,341 | - | - | Nqso (Right to Buy) | |
| Wanda M. Austin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 846 | 3,194 (0%) | 0% | 0 | Common Stock | |
| Brian J. Druker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 846 | 2,719 (0%) | 0% | 0 | Common Stock | |
| David M. Reese | EVP, Research and Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 29,050 | 29,050 | - | - | Nqso (Right to Buy) | |
| David M. Reese | EVP, Research and Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 3,469 | 41,408 (0%) | 0% | 0 | Common Stock | |
| Peter H. Griffith | EVP & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 28,341 | 28,341 | - | - | Nqso (Right to Buy) | |
| Peter H. Griffith | EVP & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 3,384 | 21,990 (0%) | 0% | 0 | Common Stock | |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 230.98 per share. | 01 May 2020 | 2,759 | 531,782 (0%) | 0% | 231.0 | 637,274 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.22 per share. | 01 May 2020 | 2,737 | 534,541 (0%) | 0% | 239.2 | 654,745 | Common Stock |
| David A. Piacquad | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.22 per share. | 01 May 2020 | 123 | 41,640 (0%) | 0% | 239.2 | 29,424 | Common Stock |
| David A. Piacquad | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 230.98 per share. | 01 May 2020 | 136 | 41,504 (0%) | 0% | 231.0 | 31,413 | Common Stock |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 230.98 per share. | 01 May 2020 | 555 | 47,356 (0%) | 0% | 231.0 | 128,194 | Common Stock |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.22 per share. | 01 May 2020 | 549 | 47,911 (0%) | 0% | 239.2 | 131,332 | Common Stock |
| Lori A Johnston | EVP, HR | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.22 per share. | 01 May 2020 | 335 | 29,307 (0%) | 0% | 239.2 | 80,139 | Common Stock |
| Cynthia M. Patton | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.22 per share. | 01 May 2020 | 115 | 24,202 (0%) | 0% | 239.2 | 27,510 | Common Stock |
| Cynthia M. Patton | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 230.98 per share. | 01 May 2020 | 127 | 24,075 (0%) | 0% | 231.0 | 29,334 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.22 per share. | 01 May 2020 | 593 | 43,243 (0%) | 0% | 239.2 | 141,857 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 230.98 per share. | 01 May 2020 | 194 | 43,049 (0%) | 0% | 231.0 | 44,810 | Common Stock |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 230.98 per share. | 01 May 2020 | 185 | 37,939 (0%) | 0% | 231.0 | 42,731 | Common Stock |
| David M. Reese | EVP, Research and Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 239.22 per share. | 01 May 2020 | 1,046 | 38,124 (0%) | 0% | 239.2 | 250,224 | Common Stock |
| Robert A. Bradway | Director, Chairman, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.28 per share. | 27 Apr 2020 | 2,543 | 537,278 (0%) | 0% | 236.3 | 600,860 | Common Stock |
| David A. Piacquad | SVP, Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.28 per share. | 27 Apr 2020 | 116 | 41,763 (0%) | 0% | 236.3 | 27,408 | Common Stock |
| Jonathan P. Graham | EVP, Gen. Counsel & Secy. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.28 per share. | 27 Apr 2020 | 548 | 48,460 (0%) | 0% | 236.3 | 129,481 | Common Stock |
| Lori A Johnston | EVP, HR | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.28 per share. | 27 Apr 2020 | 335 | 29,642 (0%) | 0% | 236.3 | 79,154 | Common Stock |
| Cynthia M. Patton | SVP & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.28 per share. | 27 Apr 2020 | 102 | 24,317 (0%) | 0% | 236.3 | 24,101 | Common Stock |
| Esteban Santos | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 236.28 per share. | 27 Apr 2020 | 526 | 43,836 (0%) | 0% | 236.3 | 124,283 | Common Stock |